NTF4 - Neurotrophin-4 - human protein (Function)
 
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Protein
Gene
References

 
NTF4 »  Neurotrophin-4  (NT-4)
 
Protein also known as:  Neutrophic factor 4.
Gene name:  NTF4
Family name: NGF-beta
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Target-derived survival factor for peripheral sensory sympathetic neurons.  
1
  • UniProtKB
GO molecular function 
Growth factor activitydefinition[GO:0008083]  
1
  • UniProtKB KW
Neurotrophin p75 receptor bindingdefinition[GO:0005166]  
1
  • RefGenome
Protein bindingdefinition[GO:0005515]  
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  • IntAct
GO biological process 
Adult locomotory behaviordefinition[GO:0008344]  
1
  • UniProtKB
Cell-cell signalingdefinition[GO:0007267]  
1
  • RefGenome
Epidermis developmentdefinition[GO:0008544]  
1
  • UniProtKB
Ganglion mother cell fate determinationdefinition[GO:0007402]  
1
  • UniProtKB
Innervationdefinition[GO:0060384] silver  
1
  • Ortholog Compara
Long-term memorydefinition[GO:0007616]  
1
  • UniProtKB
Mechanoreceptor differentiationdefinition[GO:0042490] silver  
1
  • Ortholog Compara
Negative regulation of neuron apoptotic processdefinition[GO:0043524]  
1
  • RefGenome
Neuron projection morphogenesisdefinition[GO:0048812]  
1
  • RefGenome
Regulation of neuron differentiationdefinition[GO:0045664]  
1
  • RefGenome
Sensory organ boundary specificationdefinition[GO:0008052]  
1
  • UniProtKB
Taste bud developmentdefinition[GO:0061193] silver  
1
  • Ortholog Compara
Transmembrane receptor protein tyrosine kinase signaling pathwaydefinition[GO:0007169]  
1
  • RefGenome
Pathways 
According to KEGG, this protein belongs to the following pathways:
MAPK signaling pathway  hsa04010+4909  
Neurotrophin signaling pathway  hsa04722+4909  
 

Keywords

Molecular function 
Growth factor  definition   [KW-0339]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 4909
PRO: PR:P34130