HTR7 - 5-hydroxytryptamine receptor 7 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
HTR7 »  5-hydroxytryptamine receptor 7  (5-HT7)
 
Protein also known as:  Serotonin receptor 7.
Gene name:  HTR7
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 41 3
GENE REF ISO

Function

 show evidences
Overview 
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.  
  • CuratedUniProtKB
GO molecular function 
Serotonin receptor activitydefinition[GO:0004993] silver  
  • IEAInterPro 2 GO
GO biological process 
Blood circulationdefinition[GO:0008015]  
1
  • TASPINC
Circadian rhythmdefinition[GO:0007623] silver  
  • IEAInterPro 2 GO
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerdefinition[GO:0007187]  
1
  • TASPINC
Serotonin receptor signaling pathwaydefinition[GO:0007210]  
1
  • TASGOC
Smooth muscle contractiondefinition[GO:0006939] silver  
  • IEAInterPro 2 GO
Synaptic transmissiondefinition[GO:0007268] silver  
  • IEAInterPro 2 GO
Vasoconstrictiondefinition[GO:0042310] silver  
  • IEAInterPro 2 GO
Pathways 
According to KEGG, this protein belongs to the following pathways:
Calcium signaling pathway  hsa04020+3363  
Neuroactive ligand-receptor interaction  hsa04080+3363  
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: 5-HT7_receptor
GenomeRNAi: 3363
PRO: PR:P34969
Chemistry
GuidetoPHARMACOLOGY: 12