CD79B - B-cell antigen receptor complex-associated protein beta chain - human protein (Function)
 
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Protein
Gene
References

 
CD79B »  B-cell antigen receptor complex-associated protein beta chain
 
Protein also known as:  Immunoglobulin-associated B29 protein; CD antigen CD79b.
Gene name:  CD79B
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 40 3
GENE REF ISO

Function

 show evidences
Overview 
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.  
3
  • CuratedUniProtKB
GO molecular function 
Transmembrane signaling receptor activitydefinition[GO:0004888] silver  
  • IEAInterPro 2 GO
GO biological process 
B cell receptor signaling pathwaydefinition[GO:0050853] silver  
  • IEAOrtholog Compara
Immune responsedefinition[GO:0006955]  
1
  • TASPINC
Signal transductiondefinition[GO:0007165]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
B cell receptor signaling pathway  hsa04662+974  
According to Reactome, this protein belongs to the following pathway:
Immune System  REACT_6900  
 

Keywords

Biological process 
Adaptive immunity  definition   [KW-1064]
Immunity  definition   [KW-0391]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CD79B
GenomeRNAi: 974
PRO: PR:P40259