ETV6 - Transcription factor ETV6 - human protein (Function)
 
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Protein
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ETV6 »  Transcription factor ETV6
 
Protein also known as:  ETS translocation variant 6.
Gene name:  ETV6
Family name: ETS
Entry whose protein(s) existence is based on evidence at protein level
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1 196 1
GENE REF ISO

Function

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Overview 
Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'.  
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Protein domain specific bindingdefinition[GO:0019904]  
1
  • IPIUniProtKB
RNA polymerase II regulatory region sequence-specific DNA bindingdefinition[GO:0000977]  
1
  • IDANTNU_SB
RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptiondefinition[GO:0001227]  
  • ICGO curators
Sequence-specific DNA binding RNA polymerase II transcription factor activitydefinition[GO:0000981] silver  
  • IBARefGenome
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700]  
1
  • TASPINC
GO biological process 
Cell differentiationdefinition[GO:0030154] silver  
  • IBARefGenome
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122]  
2
  • IDANTNU_SB
Regulation of transcription from RNA polymerase II promoterdefinition[GO:0006357] silver  
  • IBARefGenome
Transcription from RNA polymerase II promoterdefinition[GO:0006366] silver  
  • IBARefGenome
Pathways 
According to KEGG, this protein belongs to the following pathway:
Dorso-ventral axis formation  hsa04320+2120  
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Repressor  definition   [KW-0678]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ETV6
GenomeRNAi: 2120
PRO: PR:P41212