ECI1 - Enoyl-CoA delta isomerase 1, mitochondrial - human protein (Function)
 
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Protein
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References

 
ECI1 »  Enoyl-CoA delta isomerase 1, mitochondrial   [ EC 5.3.3.8 ]
 
Protein also known as:  Delta(3),Delta(2)-enoyl-CoA isomerase (D3,D2-enoyl-CoA isomerase).
Gene name:  ECI1
Entry whose protein(s) existence is based on evidence at protein level
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1 15 2
GENE REF ISO

Function

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Overview 
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.  
  • CuratedUniProtKB
GO molecular function 
Dodecenoyl-CoA delta-isomerase activitydefinition[GO:0004165]  
2
  • NASUniProtKB
GO biological process 
Fatty acid beta-oxidationdefinition[GO:0006635]  
1
  • NASUniProtKB
  • IEAUniPathway
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 5.3.3.8: (3Z)-dodec-3-enoyl-CoA (2E)-dodec-2-enoyl-CoA.  
1
  • CuratedUniProtKB
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathway:
Fatty acid metabolism  hsa00071+1632  
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 

Keywords

Biological process 
Fatty acid metabolism  definition   [KW-0276]
Lipid metabolism  definition   [KW-0443]
Molecular function 
Isomerase  definition   [KW-0413]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 1632
PRO: PR:P42126