DPP6 - Dipeptidyl aminopeptidase-like protein 6 - human protein (Function)
 
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DPP6 »  Dipeptidyl aminopeptidase-like protein 6
 
Protein also known as:  Dipeptidyl aminopeptidase-related protein.
Gene name:  DPP6
Family name: Peptidase S9B
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
May be involved in the physiological processes of brain function. Has no dipeptidyl aminopeptidase activity. May modulate the cell surface expression and the activity of the potassium channel KCND2.  
1
  • CuratedUniProtKB
GO molecular function 
Dipeptidyl-peptidase activitydefinition[GO:0008239]  
1
  • TASPINC
Serine-type peptidase activitydefinition[GO:0008236] silver  
  • IEAInterPro 2 GO
GO biological process 
Cell deathdefinition[GO:0008219]  
  • IEAUniProtKB KW
Neuronal action potentialdefinition[GO:0019228] silver  
  • IEAOrtholog Compara
Regulation of potassium ion transportdefinition[GO:0043266] silver  
  • IEAOrtholog Compara
Enzymatic activity 
 
More information is available from:
Note 
Genetic variation in DPP6 may influence susceptibility to amyotrophic lateral sclerosis (ALS). ALS is a severely disabling and lethal disorder caused by progressive degeneration of motor neurons in the brain, spinal cord and brainstem.  
  • CuratedUniProtKB
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: DPP6
GenomeRNAi: 1804
PRO: PR:P42658