RPS27 - 40S ribosomal protein S27 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
RPS27 »  40S ribosomal protein S27
 
Protein also known as:  Metallopan-stimulin 1 (MPS-1).
Gene name:  RPS27
Family name: Ribosomal protein S27e
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 40 1
GENE REF ISO

Function

 show evidences
GO molecular function 
DNA bindingdefinition[GO:0003677]  
1
  • NASUniProtKB
Poly(A) RNA bindingdefinition[GO:0044822]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
Structural constituent of ribosomedefinition[GO:0003735] silver  
  • IEAInterPro 2 GO
Zinc ion bindingdefinition[GO:0008270]  
1
  • NASUniProtKB
GO biological process 
Cell proliferationdefinition[GO:0008283]  
1
  • NASUniProtKB
Translationdefinition[GO:0006412]  
3
  • ICUniProtKB
Enzymatic activity 
It requires the following cofactor
Binds 1 zinc ion per subunit (Potential).  
  • CuratedUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Ribosome  hsa03010+6232  
According to Reactome, this protein belongs to the following pathways:
Eukaryotic Translation Termination  REACT_1986  
Formation of a pool of free 40S subunits  REACT_1797  
Formation of the ternary complex, and subsequently, the 43S complex  REACT_1079  
GTP hydrolysis and joining of the 60S ribosomal subunit  REACT_2085  
L13a-mediated translational silencing of Ceruloplasmin expression  REACT_79  
Mitotic Prometaphase  REACT_682  
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)  REACT_75822  
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)  REACT_75768  
Peptide chain elongation  REACT_1404  
Resolution of Sister Chromatid Cohesion  REACT_150425  
Ribosomal scanning and start codon recognition  REACT_931  
Separation of Sister Chromatids  REACT_150471  
SRP-dependent cotranslational protein targeting to membrane  REACT_115902  
Translation initiation complex formation  REACT_1979  
Viral mRNA Translation  REACT_9491  
Caution 
Was originally (PubMed8407955) thought to be a protein that could have played a role as a potentially important mediator of cellular proliferative responses to various growth factors and other environmental signals. Capable of specific binding to a cAMP response element in DNA.  
1
  • CuratedUniProtKB
 

Keywords

Molecular function 
Ribonucleoprotein  definition   [KW-0687]
Ribosomal protein  definition   [KW-0689]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: RPS27
GenomeRNAi: 6232
PRO: PR:P42677