ETV4 - ETS translocation variant 4 - human protein (Function)
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ETV4 »  ETS translocation variant 4
Protein also known as:  Polyomavirus enhancer activator 3 homolog (Protein PEA3).
Gene name:  ETV4
Family name: ETS
Entry whose protein(s) existence is based on evidence at protein level
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Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.  
  • CuratedUniProtKB
GO molecular function 
RNA polymerase II core promoter proximal region sequence-specific DNA bindingdefinition[GO:0000978]  
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptiondefinition[GO:0001077]  
  • ICGO curators
Sequence-specific DNA binding RNA polymerase II transcription factor activitydefinition[GO:0000981] silver  
  • IBARefGenome
GO biological process 
Branching involved in mammary gland duct morphogenesisdefinition[GO:0060444] silver  
  • IEAOrtholog Compara
Cell differentiationdefinition[GO:0030154] silver  
  • IBARefGenome
Motor neuron axon guidancedefinition[GO:0008045] silver  
  • IEAOrtholog Compara
Negative regulation of mammary gland epithelial cell proliferationdefinition[GO:0033600] silver  
  • IEAOrtholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944]  
  • ICGO curators
Regulation of branching involved in mammary gland duct morphogenesisdefinition[GO:0060762] silver  
  • IEAOrtholog Compara
Regulation of transcription from RNA polymerase II promoterdefinition[GO:0006357] silver  
  • IBARefGenome
Stem cell differentiationdefinition[GO:0048863] silver  
  • IEAOrtholog Compara
Transcription from RNA polymerase II promoterdefinition[GO:0006366] silver  
  • IBARefGenome


Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Technical term 
Reference proteome  definition   [KW-1185]

Further external links

GeneWiki: ETV4
GenomeRNAi: 2118
PRO: PR:P43268