ETV4 - ETS translocation variant 4 - human protein (Function)
 
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ETV4 »  ETS translocation variant 4
 
Protein also known as:  Polyomavirus enhancer activator 3 homolog (Protein PEA3).
Gene name:  ETV4
Family name: ETS
Entry whose protein(s) existence is based on evidence at protein level
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1 71 3
GENE REF ISO

Function

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Overview 
Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.  
2
  • UniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
RNA polymerase II core promoter proximal region sequence-specific DNA bindingdefinition[GO:0000978]  
1
  • NTNU_SB
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptiondefinition[GO:0001077]  
1
  • GO curators
Sequence-specific DNA binding RNA polymerase II transcription factor activitydefinition[GO:0000981]  
1
  • RefGenome
GO biological process 
Branching involved in mammary gland duct morphogenesisdefinition[GO:0060444] silver  
1
  • Ortholog Compara
Cell differentiationdefinition[GO:0030154]  
1
  • RefGenome
Motor neuron axon guidancedefinition[GO:0008045] silver  
1
  • Ortholog Compara
Negative regulation of mammary gland epithelial cell proliferationdefinition[GO:0033600] silver  
1
  • Ortholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944]  
1
  • NTNU_SB
Regulation of branching involved in mammary gland duct morphogenesisdefinition[GO:0060762] silver  
1
  • Ortholog Compara
Regulation of transcription from RNA polymerase II promoterdefinition[GO:0006357]  
1
  • RefGenome
Stem cell differentiationdefinition[GO:0048863] silver  
1
  • Ortholog Compara
Transcription from RNA polymerase II promoterdefinition[GO:0006366]  
1
  • RefGenome
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ETV4
GenomeRNAi: 2118
PRO: PR:P43268