LPAR6 - Lysophosphatidic acid receptor 6 - human protein (Function)
 
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Protein
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References

 
LPAR6 »  Lysophosphatidic acid receptor 6
 
Gene name:  LPAR6
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture.  
1
  • CuratedUniProtKB
GO molecular function 
G-protein coupled receptor activitydefinition[GO:0004930]  
  • IEAUniProtKB KW
GO biological process 
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathway:
Neuroactive ligand-receptor interaction  hsa04080+10161  
According to Reactome, this protein belongs to the following pathways:
G alpha (q) signalling events  REACT_18283  
P2Y receptors  REACT_18289  
Note 
This is a nested gene within intron 17 of the retinoblastoma gene.  
  • CuratedUniProtKB
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GenomeRNAi: 10161
PRO: PR:P43657
Chemistry
GuidetoPHARMACOLOGY: 163