XCR1 - Chemokine XC receptor 1 - human protein (Function)
 
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XCR1 »  Chemokine XC receptor 1
 
Protein also known as:  G-protein coupled receptor 5.
Gene name:  XCR1
Entry whose protein(s) existence is based on evidence at protein level
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1 22 1
GENE REF ISO

Function

 show evidences
Overview 
Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level.  
  • CuratedUniProtKB
GO molecular function 
Chemokine receptor activitydefinition[GO:0004950] silver  
  • IEAInterPro 2 GO
GO biological process 
Chemokine-mediated signaling pathwaydefinition[GO:0070098]  
1
  • TASGOC
Chemotaxisdefinition[GO:0006935] silver  
  • IEAInterPro 2 GO
Cytokine-mediated signaling pathwaydefinition[GO:0019221]  
1
  • TASGOC
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • TASPINC
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerdefinition[GO:0007187]  
1
  • TASPINC
Inflammatory responsedefinition[GO:0006954]  
1
  • TASPINC
Positive regulation of cytosolic calcium ion concentrationdefinition[GO:0007204]  
1
  • TASPINC
Release of sequestered calcium ion into cytosoldefinition[GO:0051209] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathways:
Chemokine signaling pathway  hsa04062+2829  
Cytokine-cytokine receptor interaction  hsa04060+2829  
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: XCR1
GenomeRNAi: 2829
PRO: PR:P46094
Chemistry
GuidetoPHARMACOLOGY: 75