SLCO1A2 - Solute carrier organic anion transporter family member 1A2 - human protein (Function)
 
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Protein
Gene
References

 
SLCO1A2 »  Solute carrier organic anion transporter family member 1A2
 
Protein also known as:  Sodium-independent organic anion transporter.
Gene name:  SLCO1A2
Entry whose protein(s) existence is based on evidence at transcript level
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GENE REF ISO

Function

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Overview 
Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin.  
1
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the organo anion transporter (oat) family  2.A.60.1.14  
GO molecular function 
Organic anion transmembrane transporter activitydefinition[GO:0008514]  
1
  • TASPINC
GO biological process 
Ion transmembrane transportdefinition[GO:0034220]  
1
  • TASGOC
Organic anion transportdefinition[GO:0015711]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
Bile secretion  hsa04976+6579  
According to Reactome, this protein belongs to the following pathways:
Metabolism  REACT_111217  
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: SLCO1A2
GenomeRNAi: 6579
PRO: PR:P46721
Chemistry
GuidetoPHARMACOLOGY: 1219