AVPR1B - Vasopressin V1b receptor - human protein (Function)
 
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AVPR1B »  Vasopressin V1b receptor  (V1bR)
 
Protein also known as:  Antidiuretic hormone receptor 1b.
Gene name:  AVPR1B
Entry whose protein(s) existence is based on evidence at protein level
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1 28 1
GENE REF ISO

Function

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Overview 
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the g-protein-coupled receptor (gpcr) family  9.A.14.10.2  
GO molecular function 
Protein kinase C bindingdefinition[GO:0005080]  
1
  • TASPINC
Vasopressin receptor activitydefinition[GO:0005000] silver  
  • IEAInterPro 2 GO
GO biological process 
Activation of phospholipase C activitydefinition[GO:0007202]  
1
  • TASPINC
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • TASPINC
Positive regulation of cytosolic calcium ion concentrationdefinition[GO:0007204]  
1
  • TASPINC
Regulation of systemic arterial blood pressure by vasopressindefinition[GO:0001992] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathways:
Calcium signaling pathway  hsa04020+553  
Neuroactive ligand-receptor interaction  hsa04080+553  
Vascular smooth muscle contraction  hsa04270+553  
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: Arginine_vasopressin_receptor_1B
GenomeRNAi: 553
PRO: PR:P47901
Chemistry
GuidetoPHARMACOLOGY: 367