SLC6A9 - Sodium- and chloride-dependent glycine transporter 1 - human protein (Function)
 
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Protein
Gene
References

 
SLC6A9 »  Sodium- and chloride-dependent glycine transporter 1  (GlyT1)
 
Protein also known as:  Solute carrier family 6 member 9.
Gene name:  SLC6A9
Entry whose protein(s) existence is based on evidence at protein level
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1 25 3
GENE REF ISO

Function

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Overview 
Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the neurotransmitter:sodium symporter (nss) family  2.A.22.2.12  
GO molecular function 
Glycine:sodium symporter activitydefinition[GO:0015375]  
1
  • TASPINC
Neurotransmitter:sodium symporter activitydefinition[GO:0005328] silver  
  • IEAInterPro 2 GO
GO biological process 
Transportdefinition[GO:0006810]  
1
  • TASPINC
Pathways 
According to Reactome, this protein belongs to the following pathways:
Amine compound SLC transporters  REACT_20679  
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Amino-acid transport  definition   [KW-0029]
Neurotransmitter transport  definition   [KW-0532]
Symport  definition   [KW-0769]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: Glycine_transporter_1
GenomeRNAi: 6536
PRO: PR:P48067
Chemistry
GuidetoPHARMACOLOGY: 935