SLC4A3 - Anion exchange protein 3 - human protein (Function)
 
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SLC4A3 »  Anion exchange protein 3  (AE 3)
 
Protein also known as:  Cardiac/brain band 3-like protein.
Gene name:  SLC4A3
Entry whose protein(s) existence is based on evidence at protein level
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1 29 3
GENE REF ISO

Function

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Overview 
Plasma membrane anion exchange protein of wide distribution. Mediates at least a part of the Cl(-)/HCO3(-) exchange in cardiac myocytes. Both BAE3 and CAE3 forms transport Cl(-).  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the anion exchanger (ae) family  2.A.31.1.3  
GO molecular function 
Inorganic anion exchanger activitydefinition[GO:0005452] silver  
  • IEAInterPro 2 GO
GO biological process 
Regulation of intracellular pHdefinition[GO:0051453] silver  
  • IEAOrtholog Compara
Transportdefinition[GO:0006810]  
1
  • TASPINC
Pathways 
According to Reactome, this protein belongs to the following pathway:
Bicarbonate transporters  REACT_19298  
 

Keywords

Biological process 
Anion exchange  definition   [KW-0039]
Antiport  definition   [KW-0050]
Ion transport  definition   [KW-0406]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SLC4A3
GenomeRNAi: 6508
PRO: PR:P48751