TNNI2 - Troponin I, fast skeletal muscle - human protein (Function)
 
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TNNI2 »  Troponin I, fast skeletal muscle
 
Protein also known as:  Troponin I, fast-twitch isoform.
Gene name:  TNNI2
Family name: Troponin I
Entry whose protein(s) existence is based on evidence at protein level
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1 19 2
GENE REF ISO

Function

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Overview 
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.  
  • CuratedUniProtKB
GO molecular function 
Contributes to actin bindingdefinition[GO:0003779]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
Troponin T bindingdefinition[GO:0031014]  
1
  • IPIUniProtKB
GO biological process 
Positive regulation of transcription, DNA-templateddefinition[GO:0045893]  
1
  • IDAUniProtKB
Skeletal muscle contractiondefinition[GO:0003009]  
1
  • IDAUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathway:
Muscle contraction  REACT_17044  
 

Keywords

Molecular function 
Muscle protein  definition   [KW-0514]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: TNNI2
GenomeRNAi: 7136
PRO: PR:P48788