PTH2R - Parathyroid hormone 2 receptor - human protein (Function)
 
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PTH2R »  Parathyroid hormone 2 receptor  (PTH2 receptor)
 
Gene name:  PTH2R
Entry whose protein(s) existence is based on evidence at protein level
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1 24 1
GENE REF ISO

Function

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Overview 
This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Parathyroid hormone receptor activitydefinition[GO:0004991]  
1
  • TASPINC
GO biological process 
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
Neuroactive ligand-receptor interaction  hsa04080+5746  
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: Parathyroid_hormone_2_receptor
GenomeRNAi: 5746
PRO: PR:P49190
Chemistry
GuidetoPHARMACOLOGY: 332