HARS2 - Probable histidine--tRNA ligase, mitochondrial - human protein (Function)
 
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Protein
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References

 
HARS2 »  Probable histidine--tRNA ligase, mitochondrial   [ EC 6.1.1.21 ]
 
Protein also known as:  Histidine--tRNA ligase-like.
Gene name:  HARS2
Entry whose protein(s) existence is based on evidence at protein level
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1 21 2
GENE REF ISO

Function

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GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Histidine-tRNA ligase activitydefinition[GO:0004821]  
1
  • NASUniProtKB
Poly(A) RNA bindingdefinition[GO:0044822]  
1
  • IDAUniProtKB
GO biological process 
Histidyl-tRNA aminoacylationdefinition[GO:0006427] silver  
  • IEAInterPro 2 GO
Translationdefinition[GO:0006412]  
1
  • NASUniProtKB
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 6.1.1.21: ATP + L-histidine + tRNA(His) AMP + diphosphate + L-histidyl-tRNA(His).  
  • CuratedUniProtKB
 
More information is available from:
Pathways 
According to KEGG, this protein belongs to the following pathway:
Aminoacyl-tRNA biosynthesis  hsa00970+23438  
According to Reactome, this protein belongs to the following pathway:
Mitochondrial tRNA aminoacylation  REACT_15302  
 

Keywords

Biological process 
Protein biosynthesis  definition   [KW-0648]
Molecular function 
Aminoacyl-tRNA synthetase  definition   [KW-0030]
Ligase  definition   [KW-0436]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: HARS2
GenomeRNAi: 23438
PRO: PR:P49590