NPY4R - Neuropeptide Y receptor type 4 - human protein (Function)
 
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NPY4R »  Neuropeptide Y receptor type 4  (NPY4-R)
 
Protein also known as:  Pancreatic polypeptide receptor 1 (PP1).
Gene name:  NPY4R
Entry whose protein(s) existence is based on evidence at transcript level
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1 28 1
GENE REF ISO

Function

 show evidences
Overview 
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13-36) > PP (31-36) > NPY free acid.  
  • CuratedUniProtKB
GO molecular function 
G-protein coupled receptor activitydefinition[GO:0004930]  
1
  • TASPINC
Pancreatic polypeptide receptor activitydefinition[GO:0001602] silver  
  • IEAOrtholog Compara
Peptide bindingdefinition[GO:0042277] silver  
  • IEAOrtholog Compara
Peptide YY receptor activitydefinition[GO:0001601] silver  
  • IEAOrtholog Compara
GO biological process 
Blood circulationdefinition[GO:0008015]  
1
  • TASPINC
Digestiondefinition[GO:0007586]  
1
  • TASPINC
Feeding behaviordefinition[GO:0007631]  
1
  • TASPINC
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • TASPINC
Neuropeptide signaling pathwaydefinition[GO:0007218]  
  • IEAInterPro 2 GO
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
Neuroactive ligand-receptor interaction  hsa04080+5540  
According to Reactome, this protein belongs to the following pathways:
G alpha (i) signalling events  REACT_19231  
Peptide ligand-binding receptors  REACT_14819  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: Pancreatic_polypeptide_receptor_1
PRO: PR:P50391
Chemistry
GuidetoPHARMACOLOGY: 307