ATP4B - Potassium-transporting ATPase subunit beta - human protein (Function)
 
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Protein
Gene
References

 
ATP4B »  Potassium-transporting ATPase subunit beta
 
Protein also known as:  Gastric H(+)/K(+) ATPase subunit beta.
Gene name:  ATP4B
Entry whose protein(s) existence is based on evidence at protein level
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1 19 1
GENE REF ISO

Function

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Overview 
Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity.  
2
  • UniProtKB
According to TCDB this is a transporter from family:
the p-type atpase (p-atpase) superfamily  3.A.3.1.2  
GO molecular function 
Hydrogen:potassium-exchanging ATPase activitydefinition[GO:0008900]  
1
  • PINC
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
GO biological process 
Cell adhesiondefinition[GO:0007155]  
1
  • UniProtKB KW
Hydrogen ion transmembrane transportdefinition[GO:1902600]  
1
  • GOC
Potassium ion transportdefinition[GO:0006813]  
1
  • UniProtKB KW
Response to lipopolysaccharidedefinition[GO:0032496] silver  
1
  • Ortholog Compara
Response to organonitrogen compounddefinition[GO:0010243] silver  
1
  • Ortholog Compara
Sodium ion transportdefinition[GO:0006814] silver  
1
  • InterPro 2 GO
Pathways 
According to KEGG, this protein belongs to the following pathways:
Collecting duct acid secretion  hsa04966+496  
Gastric acid secretion  hsa04971+496  
Oxidative phosphorylation  hsa00190+496  
According to Reactome, this protein belongs to the following pathway:
Ion transport by P-type ATPases  REACT_25149  
 
More information is available from:
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Hydrogen ion transport  definition   [KW-0375]
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 496
PRO: PR:P51164