BCAP31 - B-cell receptor-associated protein 31 - human protein (Function)
 
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BCAP31 »  B-cell receptor-associated protein 31  (Bap31)
 
Protein also known as:  6C6-AG tumor-associated antigen.
Gene name:  BCAP31
Family name: BCAP29/BCAP31
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 35 2
GENE REF ISO

Function

 show evidences
Overview 
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis.  
2
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the general secretory pathway (sec) family  3.A.5.9.1  
GO molecular function 
Protein bindingdefinition[GO:0005515]  
4
  • IPIIntAct
  • IPIUniProtKB
GO biological process 
Calcium-mediated signaling using intracellular calcium sourcedefinition[GO:0035584]  
1
  • IMPUniProtKB
Immune responsedefinition[GO:0006955] silver  
  • IEAOrtholog Compara
Intracellular protein transportdefinition[GO:0006886] silver  
  • IEAInterPro 2 GO
Negative regulation of endoplasmic reticulum calcium ion concentrationdefinition[GO:0032471]  
1
  • IMPUniProtKB
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic processdefinition[GO:0043280]  
1
  • IMPUniProtKB
Positive regulation of cytosolic calcium ion concentrationdefinition[GO:0007204]  
1
  • IMPUniProtKB
Positive regulation of intrinsic apoptotic signaling pathwaydefinition[GO:2001244]  
1
  • IMPUniProtKB
Positive regulation of mitochondrial calcium ion concentrationdefinition[GO:0051561]  
1
  • IMPUniProtKB
Spermatogenesisdefinition[GO:0007283] silver  
  • IEAOrtholog Compara
Vesicle-mediated transportdefinition[GO:0016192]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathway:
Protein processing in endoplasmic reticulum  hsa04141+10134  
According to Reactome, this protein belongs to the following pathways:
Apoptosis  REACT_578  
Immune System  REACT_6900  
 

Keywords

Biological process 
Apoptosis  definition   [KW-0053]
ER-Golgi transport  definition   [KW-0931]
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: BCAP31
GenomeRNAi: 10134
PRO: PR:P51572