P2RY4 - P2Y purinoceptor 4 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
P2RY4 »  P2Y purinoceptor 4
 
Gene name:  P2RY4
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 20 1
GENE REF ISO

Function

 show evidences
Overview 
Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP.  
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524] silver  
  • IEAOrtholog Compara
G-protein coupled purinergic nucleotide receptor activitydefinition[GO:0045028] silver  
  • IEAInterPro 2 GO
Uridine nucleotide receptor activitydefinition[GO:0015065]  
1
  • TASPINC
UTP-activated nucleotide receptor activitydefinition[GO:0045030] silver  
  • IEAOrtholog Compara
GO biological process 
G-protein coupled purinergic nucleotide receptor signaling pathwaydefinition[GO:0035589]  
  • IEAInterPro 2 GO
Phospholipase C-activating G-protein coupled receptor signaling pathwaydefinition[GO:0007200]  
1
  • TASPINC
Positive regulation of cytosolic calcium ion concentrationdefinition[GO:0007204]  
1
  • TASPINC
Transepithelial chloride transportdefinition[GO:0030321] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
Neuroactive ligand-receptor interaction  hsa04080+5030  
According to Reactome, this protein belongs to the following pathways:
G alpha (i) signalling events  REACT_19231  
P2Y receptors  REACT_18289  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: P2RY4
GenomeRNAi: 5030
PRO: PR:P51582
Chemistry
GuidetoPHARMACOLOGY: 325