NEK4 - Serine/threonine-protein kinase Nek4 - human protein (Function)
 
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NEK4 »  Serine/threonine-protein kinase Nek4   [ EC 2.7.11.1 ]
 
Protein also known as:  Serine/threonine-protein kinase NRK2.
Gene name:  NEK4
Entry whose protein(s) existence is based on evidence at protein level
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1 20 3
GENE REF ISO

Function

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Overview 
Seems to act exclusively upon threonine residues (By similarity).  
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
Protein serine/threonine kinase activitydefinition[GO:0004674]  
1
  • TASPINC
Receptor signaling protein serine/threonine kinase activitydefinition[GO:0004702] silver  
  • IBARefGenome
GO biological process 
Intracellular signal transductiondefinition[GO:0035556] silver  
  • IBARefGenome
Mitosisdefinition[GO:0007067]  
  • IEAUniProtKB KW
Protein phosphorylationdefinition[GO:0006468]  
1
  • TASPINC
Signal transductiondefinition[GO:0007165] silver  
  • IBARefGenome
Signal transduction by phosphorylationdefinition[GO:0023014] silver  
  • IBARefGenome
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.11.1: ATP + a protein ADP + a phosphoprotein.  
  • CuratedUniProtKB
It requires the following cofactor
Magnesium (By similarity).  
  • CuratedUniProtKB
 

Keywords

Biological process 
Cell cycle  definition   [KW-0131]
Cell division  definition   [KW-0132]
Mitosis  definition   [KW-0498]
Molecular function 
Kinase  definition   [KW-0418]
Serine/threonine-protein kinase  definition   [KW-0723]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GenomeRNAi: 6787
PRO: PR:P51957
Chemistry
GuidetoPHARMACOLOGY: 2119