SLC7A2 - Low affinity cationic amino acid transporter 2 - human protein (Function)
 
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Protein
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SLC7A2 »  Low affinity cationic amino acid transporter 2  (CAT2)
 
Protein also known as:  Solute carrier family 7 member 2.
Gene name:  SLC7A2
Entry whose protein(s) existence is based on evidence at protein level
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1 33 3
GENE REF ISO

Function

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Overview 
Low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). Plays a regulatory role in classical or alternative activation of macrophages (By similarity).  
1
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the amino acid-polyamine-organocation (apc) family  2.A.3.3.8  
GO molecular function 
Basic amino acid transmembrane transporter activitydefinition[GO:0015174]  
1
  • TASPINC
High affinity arginine transmembrane transporter activitydefinition[GO:0005289] silver  
  • IEAOrtholog Compara
L-lysine transmembrane transporter activitydefinition[GO:0015189] silver  
  • IEAOrtholog Compara
L-ornithine transmembrane transporter activitydefinition[GO:0000064] silver  
  • IEAOrtholog Compara
GO biological process 
Arginine transportdefinition[GO:0015809] silver  
  • IEAOrtholog Compara
Cellular amino acid metabolic processdefinition[GO:0006520]  
1
  • TASPINC
L-alpha-amino acid transmembrane transportdefinition[GO:1902475]  
  • IEAOrtholog Compara
Lysine transportdefinition[GO:0015819] silver  
  • IEAOrtholog Compara
Macrophage activationdefinition[GO:0042116] silver  
  • IEAOrtholog Compara
Nitric oxide biosynthetic processdefinition[GO:0006809] silver  
  • IEAOrtholog Compara
Nitric oxide production involved in inflammatory responsedefinition[GO:0002537] silver  
  • IEAOrtholog Compara
Ornithine transportdefinition[GO:0015822] silver  
  • IEAOrtholog Compara
Regulation of inflammatory responsedefinition[GO:0050727] silver  
  • IEAOrtholog Compara
Regulation of macrophage activationdefinition[GO:0043030] silver  
  • IEAOrtholog Compara
Transportdefinition[GO:0006810]  
1
  • TASPINC
Pathways 
According to Reactome, this protein belongs to the following pathway:
Amino acid transport across the plasma membrane  REACT_13796  
 

Keywords

Biological process 
Amino-acid transport  definition   [KW-0029]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SLC7A2
GenomeRNAi: 6542
PRO: PR:P52569