ART1 - GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 - human protein (Function)
 
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ART1 »  GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
 
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    Protein also known as:  ADP-ribosyltransferase C2 and C3 toxin-like 1 (ARTC1); CD antigen CD296.
    Gene name:  ART1
    Family name: Arg-specific ADP-ribosyltransferase
    This protein has been shown to exist at transcript level
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    GENE REF ISO

    Function

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    Overview 
    Has ADP-ribosyltransferase activity toward GLP1R.  
    1
    ref
    • CuratedUniProtKB
    GO molecular function 
    NAD(P)+-protein-arginine ADP-ribosyltransferase activitydefinition[GO:0003956]  
    • IEAEC 2 GO
    NAD+ ADP-ribosyltransferase activitydefinition[GO:0003950] ‹silver  
    • IEAOrtholog Compara
    GO biological process 
    Protein ADP-ribosylationdefinition[GO:0006471] ‹silver  
    • IEAInterPro 2 GO
    Enzymatic activity 
    This protein acts as an enzyme. It is known to catalyze the following reactions
    NAD(+) + protein-L-arginine ⇄ nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine.  
    • CuratedUniProtKB
    NADP(+) + protein-L-arginine ⇄ nicotinamide + N(omega)-((2'-phospho-ADP)-D-ribosyl)-protein-L-arginine.  
    • CuratedUniProtKB
    Pathways 
    According to Reactome, this protein belongs to the following pathway:
    Immune System  REACT_6900  
     

    Keywords

    Molecular function 
    Glycosyltransferase  definition   [KW-0328]
    Transferase  definition   [KW-0808]
    Technical term 
    Reference proteome  definition   [KW-1185]
     

    neXtProt

    SIB  Genebio