ART1 - GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 - human protein (Function)
 
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Protein
Gene
References

 
ART1 »  GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1   [ EC 2.4.2.31 ]
 
Protein also known as:  ADP-ribosyltransferase C2 and C3 toxin-like 1 (ARTC1); CD antigen CD296.
Gene name:  ART1
Entry whose protein(s) existence is based on evidence at transcript level
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1 15 1
GENE REF ISO

Function

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Overview 
Has ADP-ribosyltransferase activity toward GLP1R.  
1
  • CuratedUniProtKB
GO molecular function 
NAD(P)+-protein-arginine ADP-ribosyltransferase activitydefinition[GO:0003956]  
  • IEAEC 2 GO
NAD+ ADP-ribosyltransferase activitydefinition[GO:0003950] silver  
  • IEAOrtholog Compara
GO biological process 
Protein ADP-ribosylationdefinition[GO:0006471] silver  
  • IEAInterPro 2 GO
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.4.2.31: NAD(+) + protein-L-arginine nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine.  
  • CuratedUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathway:
Alpha-defensins  REACT_115574  
 

Keywords

Molecular function 
Glycosyltransferase  definition   [KW-0328]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 417
PRO: PR:P52961