SLC25A1 - Tricarboxylate transport protein, mitochondrial - human protein (Function)
 
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Protein
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References

 
SLC25A1 »  Tricarboxylate transport protein, mitochondrial
 
Protein also known as:  Solute carrier family 25 member 1.
Gene name:  SLC25A1
Entry whose protein(s) existence is based on evidence at protein level
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1 23 1
GENE REF ISO

Function

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Overview 
Involved in citrate-H(+)/malate exchange. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the mitochondrial carrier (mc) family  2.A.29.7.2  
GO molecular function 
Citrate transmembrane transporter activitydefinition[GO:0015137]  
1
  • TASUniProtKB
GO biological process 
Citrate transportdefinition[GO:0015746]  
1
  • TASGOC
Transmembrane transportdefinition[GO:0055085] silver  
  • IEAInterPro 2 GO
Pathways 
According to Reactome, this protein belongs to the following pathways:
Fatty Acyl-CoA Biosynthesis  REACT_1319  
Gluconeogenesis  REACT_1520  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: SLC25A1
GenomeRNAi: 6576
PRO: PR:P53007
Chemistry
GuidetoPHARMACOLOGY: 1051