SLC5A3 - Sodium/myo-inositol cotransporter - human protein (Function)
 
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Protein
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SLC5A3 »  Sodium/myo-inositol cotransporter
 
Gene name:  SLC5A3
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the solute:sodium symporter (sss) family  2.A.21.3.14  
GO molecular function 
Myo-inositol:sodium symporter activitydefinition[GO:0005367]  
1
  • TASPINC
GO biological process 
Myo-inositol transportdefinition[GO:0015798]  
1
  • TASGOC
Sodium ion transportdefinition[GO:0006814]  
  • IEAUniProtKB KW
Transportdefinition[GO:0006810]  
1
  • TASPINC
Pathways 
According to Reactome, this protein belongs to the following pathways:
Hexose transport  REACT_9441  
Inositol transporters  REACT_19188  
Na+-dependent glucose transporters  REACT_19165  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Sodium transport  definition   [KW-0739]
Symport  definition   [KW-0769]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GenomeRNAi: 6526
PRO: PR:P53794
Chemistry
GuidetoPHARMACOLOGY: 924