ATN1 - Atrophin-1 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
ATN1 »  Atrophin-1
 
Protein also known as:  Dentatorubral-pallidoluysian atrophy protein.
Gene name:  ATN1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 76 1
GENE REF ISO

Function

 show evidences
Overview 
Transcriptional corepressor. Recruits NR2E1 to repress transcription. Promotes vascular smooth cell (VSMC) migration and orientation (By similarity). Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of poly-Asn (polyQ) repeats.  
3
  • UniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
5
  • UniProtKB
  • IntAct
Protein domain specific bindingdefinition[GO:0019904]  
1
  • UniProtKB
Toxin receptor bindingdefinition[GO:0050827] silver  
1
  • Ortholog Compara
Transcription corepressor activitydefinition[GO:0003714]  
1
  • UniProtKB
GO biological process 
Cell migrationdefinition[GO:0016477] silver  
1
  • Ortholog Compara
Central nervous system developmentdefinition[GO:0007417]  
1
  • PINC
Maintenance of cell polaritydefinition[GO:0030011] silver  
1
  • Ortholog Compara
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122]  
1
  • UniProtKB
Neuron apoptotic processdefinition[GO:0051402]  
1
  • UniProtKB
Toxin metabolic processdefinition[GO:0009404] silver  
1
  • Ortholog Compara
Transcription, DNA-templateddefinition[GO:0006351]  
1
  • UniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ATN1
GenomeRNAi: 1822
PRO: PR:P54259