ADPRH - [Protein ADP-ribosylarginine] hydrolase - human protein (Function)
 
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ADPRH »  [Protein ADP-ribosylarginine] hydrolase   [ EC 3.2.2.19 ]  (ADP-ribosylarginine hydrolase)
 
Protein also known as:  ADP-ribose-L-arginine cleaving enzyme.
Gene name:  ADPRH
Entry whose protein(s) existence is based on evidence at protein level
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1 13 1
GENE REF ISO

Function

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Overview 
Catalyzes the reverse reaction of mono-ADP-ribosylation.  
  • CuratedUniProtKB
GO molecular function 
ADP-ribosylarginine hydrolase activitydefinition[GO:0003875]  
1
  • IMPUniProtKB
Magnesium ion bindingdefinition[GO:0000287] silver  
  • IEAInterPro 2 GO
GO biological process 
Cellular protein modification processdefinition[GO:0006464]  
1
  • IMPUniProtKB
Protein de-ADP-ribosylationdefinition[GO:0051725] silver  
  • IEAInterPro 2 GO
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reactions
Protein-N(omega)-(ADP-D-ribosyl)-L-arginine + H(2)O ADP-D-ribose + protein-L-arginine.  
  • CuratedUniProtKB
N(omega)-(ADP-D-ribosyl)-L-arginine + H(2)O ADP-D-ribose + L-arginine.  
  • CuratedUniProtKB
 

Keywords

Molecular function 
Hydrolase  definition   [KW-0378]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 141
PRO: PR:P54922