GEM - GTP-binding protein GEM - human protein (Sequence)
 
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GEM »  GTP-binding protein GEM
 
Protein also known as:  GTP-binding mitogen-induced T-cell protein.
Gene name:  GEM
Family name: Small GTPase » RGK
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 25 1
GENE REF ISO

Displayed isoform: Iso 1

 
 
Isoform Iso 1   296 aaMass: 33949 Da,  pI: 8.77
MTLNNVTMRQ GTVGMQPQQQ RWSIPADGRH LMVQKEPHQY SHRNRHSATP EDHCRRSWSS DSTDSVISSE SGNTYYRVVL IGEQGVGKST LANIFAGVHD SMDSDCEVLG EDTYERTLMV DGESATIILL DMWENKGENE WLHDHCMQVG DAYLIVYSIT DRASFEKASE LRIQLRRARQ TEDIPIILVG NKSDLVRCRE VSVSEGRACA VVFDCKFIET SAAVQHNVKE LFEGIVRQVR LRRDSKEKNE RRLAYQKRKE SMPRKARRFW GKIVAKNNKN MAFKLKSKSC HDLSVL

Sequence

 show evidences
PTM 
Phosphorylated on tyrosine residues.  
  • CuratedUniProtKB
 

Keywords

Coding sequence diversity 
Polymorphism  definition   [KW-0621]
PTM 
Phosphoprotein  definition   [KW-0597]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Family and domain databases
InterPro: IPR027417 [ P-loop NTPase ]
InterPro: IPR005225 [ Small GTP-bd dom ]
InterPro: IPR001806 [ Small GTPase ]
InterPro: IPR020849 [ Small GTPase Ras ]
InterPro: IPR017358 [ Small GTPase GEM/REM/Rad ]
PANTHER: PTHR24070 [ PTHR24070 ]
Pfam: PF00071 [ Ras ]
PIRSF: PIRSF038017 [ GTP-binding GEM ]
PRINTS: PR00449 [ RASTRNSFRMNG ]
PROSITE: PS51421 [ RAS ]
SUPFAM: SSF52540 [ SSF52540 ]
TIGRFAMs: TIGR00231 [ small GTP ]
Genome annotation databases
Ensembl: Transcript: ENST00000297596;  Protein: ENSP00000297596;  Gene: ENSG00000164949.
Ensembl: Transcript: ENST00000396194;  Protein: ENSP00000379497;  Gene: ENSG00000164949.
Ensembl: Transcript: ENST00000523433;  Protein: ENSP00000428258;  Gene: ENSG00000164949.
KEGG: hsa:2669
UCSC: uc003ygi.3
Organism-specific databases
MGI: MGI:99844 [ Gem ]
Other
EvolutionaryTrace: P55040
PTM databases
PhosphoSite: P55040
Phylogenomic databases
eggNOG: COG1100
HOGENOM: HOG000246961
HOVERGEN: HBG104899
InParanoid: P55040
KO: K07846
OMA: APEDHCR
OrthoDB: EOG7Q8CP8
PhylomeDB: P55040
Sequence databases
CCDS: CCDS6261.1 [ P55040-1 ]
EMBL: mRNA:  BC022010 . Translation:  AAH22010.1 .
EMBL: mRNA:  U13052 . Translation:  AAC50067.1 .
EMBL: mRNA:  AK314017 . Translation:  BAG36728.1 .
EMBL: mRNA:  U10550 . Translation:  AAA64911.1 .
EMBL: Genomic DNA:  CH471060 . Translation:  EAW91709.1 .
IPI: IPI00022710
PIR: I38745
PIR: A54575
RefSeq: Protein:  NP_005252.1. Nucleotide sequence:  NM_005261.3.
RefSeq: Protein:  NP_859053.1. Nucleotide sequence:  NM_181702.2.
UniProtKB: P55040 [ GEM ]
Protocols and materials databases
DNASU: 2669