MARS - Methionine--tRNA ligase, cytoplasmic - human protein (Function)
 
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Protein
Gene
References

 
MARS »  Methionine--tRNA ligase, cytoplasmic   [ EC 6.1.1.10 ]
 
Protein also known as:  Methionyl-tRNA synthetase (MetRS).
Gene name:  MARS
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
tRNA bindingdefinition[GO:0000049]  
  • IEAUniProtKB KW
GO biological process 
Methionyl-tRNA aminoacylationdefinition[GO:0006431] silver  
  • IEAInterPro 2 GO
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 6.1.1.10: ATP + L-methionine + tRNA(Met) AMP + diphosphate + L-methionyl-tRNA(Met).  
  • CuratedUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
Aminoacyl-tRNA biosynthesis  hsa00970+4141  
Selenocompound metabolism  hsa00450+4141  
According to Reactome, this protein belongs to the following pathway:
Gene Expression  REACT_71  
 

Keywords

Biological process 
Protein biosynthesis  definition   [KW-0648]
Molecular function 
Aminoacyl-tRNA synthetase  definition   [KW-0030]
Ligase  definition   [KW-0436]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: MARS_(gene)
GenomeRNAi: 4141
PRO: PR:P56192