AP1S2 - AP-1 complex subunit sigma-2 - human protein (Function)
 
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Protein
Gene
References

 
AP1S2 »  AP-1 complex subunit sigma-2
 
Protein also known as:  Clathrin assembly protein complex 1 sigma-1B small chain.
Gene name:  AP1S2
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.  
  • CuratedUniProtKB
GO molecular function 
Protein transporter activitydefinition[GO:0008565] silver  
  • IEAInterPro 2 GO
GO biological process 
Intracellular protein transportdefinition[GO:0006886] silver  
  • IEAInterPro 2 GO
Pathways 
According to KEGG, this protein belongs to the following pathway:
Lysosome  hsa04142+8905  
According to Reactome, this protein belongs to the following pathways:
Disease  REACT_116125  
Immune System  REACT_6900  
Membrane Trafficking  REACT_11123  
 

Keywords

Biological process 
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: AP1S2
GenomeRNAi: 8905
PRO: PR:P56377