NDUFA6 - NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 - human protein (Function)
 
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References

 
NDUFA6 »  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
 
Protein also known as:  NADH-ubiquinone oxidoreductase B14 subunit.
Gene name:  NDUFA6
Family name: Complex I LYR
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 18 1
GENE REF ISO

Function

 show evidences
Overview 
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.  
  • CuratedUniProtKB
GO molecular function 
NADH dehydrogenase (ubiquinone) activitydefinition[GO:0008137]  
1
  • NASUniProtKB
GO biological process 
Mitochondrial electron transport, NADH to ubiquinonedefinition[GO:0006120]  
1
  • NASUniProtKB
Response to oxidative stressdefinition[GO:0006979]  
1
  • IDAUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
Alzheimer's disease  hsa05010+4700  
Huntington's disease  hsa05016+4700  
Metabolic pathways  hsa01100+4700  
Oxidative phosphorylation  hsa00190+4700  
Parkinson's disease  hsa05012+4700  
According to Reactome, this protein belongs to the following pathway:
Respiratory electron transport  REACT_22393  
 

Keywords

Biological process 
Electron transport  definition   [KW-0249]
Respiratory chain  definition   [KW-0679]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: NDUFA6
GenomeRNAi: 4700
PRO: PR:P56556