PIGP - Phosphatidylinositol N-acetylglucosaminyltransferase subunit P - human protein (Function)
 
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PIGP »  Phosphatidylinositol N-acetylglucosaminyltransferase subunit P   [ EC 2.4.1.198 ]
 
Protein also known as:  Phosphatidylinositol-glycan biosynthesis class P protein (PIG-P).
Gene name:  PIGP
Family name: PIGP
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 13 3
GENE REF ISO

Function

 show evidences
Overview 
Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.  
1
  • CuratedUniProtKB
GO molecular function 
Contributes to phosphatidylinositol N-acetylglucosaminyltransferase activitydefinition[GO:0017176]  
1
  • IDAMGI
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.4.1.198: UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.  
  • CuratedUniProtKB
 
More information is available from:
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis  hsa00563+51227  
Metabolic pathways  hsa01100+51227  
According to Reactome, this protein belongs to the following pathway:
Synthesis of glycosylphosphatidylinositol (GPI)  REACT_952  
 

Keywords

Biological process 
GPI-anchor biosynthesis  definition   [KW-0337]
Molecular function 
Glycosyltransferase  definition   [KW-0328]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: PIGP
GenomeRNAi: 51227
PRO: PR:P57054