TAS2R38 - Taste receptor type 2 member 38 - human protein (Function)
 
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Protein
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TAS2R38 »  Taste receptor type 2 member 38  (T2R38)
 
Protein also known as:  Taste receptor type 2 member 61 (T2R61).
Gene name:  TAS2R38
Entry whose protein(s) existence is based on evidence at transcript level
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1 52 1
GENE REF ISO

Function

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Overview 
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).  
  • CuratedUniProtKB
GO molecular function 
G-protein coupled receptor activitydefinition[GO:0004930]  
  • IEAUniProtKB KW
GO biological process 
Sensory perception of tastedefinition[GO:0050909]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathway:
Taste transduction  hsa04742+5726  
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
Note 
Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.  
  • CuratedUniProtKB
 

Keywords

Biological process 
Sensory transduction  definition   [KW-0716]
Taste  definition   [KW-0919]
Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: TAS2R38
GenomeRNAi: 5726
PRO: PR:P59533