TAS2R40 - Taste receptor type 2 member 40 - human protein (Function)
 
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Protein
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References

 
TAS2R40 »  Taste receptor type 2 member 40  (T2R40)
 
Protein also known as:  Taste receptor type 2 member 58 (T2R58).
Gene name:  TAS2R40
Entry whose protein(s) existence is based on evidence at transcript level
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GENE REF ISO

Function

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Overview 
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.  
  • CuratedUniProtKB
GO molecular function 
G-protein coupled receptor activitydefinition[GO:0004930]  
  • IEAUniProtKB KW
GO biological process 
Sensory perception of tastedefinition[GO:0050909]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathway:
Taste transduction  hsa04742+259286  
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
Note 
Several bitter taste receptors are expressed in a single taste receptor cell.  
  • CuratedUniProtKB
 

Keywords

Biological process 
Sensory transduction  definition   [KW-0716]
Taste  definition   [KW-0919]
Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: TAS2R40
GenomeRNAi: 259286
PRO: PR:P59535