SEC61B - Protein transport protein Sec61 subunit beta - human protein (Function)
 
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SEC61B »  Protein transport protein Sec61 subunit beta
 
Gene name:  SEC61B
Family name: SEC61-beta
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Necessary for protein translocation in the endoplasmic reticulum.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the general secretory pathway (sec) family  3.A.5.9.1  
GO molecular function 
Epidermal growth factor bindingdefinition[GO:0048408]  
1
  • IPIUniProtKB
Poly(A) RNA bindingdefinition[GO:0044822]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
  • IPIUniProtKB
Ribosome bindingdefinition[GO:0043022] silver  
  • IEAOrtholog Compara
GO biological process 
ER-associated ubiquitin-dependent protein catabolic processdefinition[GO:0030433]  
1
  • IDAUniProtKB
Protein import into nucleus, translocationdefinition[GO:0000060]  
1
  • IMPUniProtKB
Retrograde protein transport, ER to cytosoldefinition[GO:0030970]  
1
  • IMPUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
Phagosome  hsa04145+10952  
Protein export  hsa03060+10952  
Protein processing in endoplasmic reticulum  hsa04141+10952  
Vibrio cholerae infection  hsa05110+10952  
According to Reactome, this protein belongs to the following pathways:
Gene Expression  REACT_71  
Immune System  REACT_6900  
Metabolism of proteins  REACT_17015  
 

Keywords

Biological process 
Protein transport  definition   [KW-0653]
Translocation  definition   [KW-0811]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SEC61B
GenomeRNAi: 10952
PRO: PR:P60468