RPL37 - 60S ribosomal protein L37 - human protein (Function)
 
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Protein
Gene
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RPL37 »  60S ribosomal protein L37
 
Protein also known as:  G1.16.
Gene name:  RPL37
Family name: Ribosomal protein L37e
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Binds to the 23S rRNA.  
1
  • UniProtKB
GO molecular function 
Metal ion bindingdefinition[GO:0046872]  
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  • UniProtKB KW
RNA bindingdefinition[GO:0003723]  
1
  • UniProtKB
rRNA bindingdefinition[GO:0019843]  
1
  • UniProtKB KW
Structural constituent of ribosomedefinition[GO:0003735]  
2
  • UniProtKB
GO biological process 
Translationdefinition[GO:0006412]  
2
  • UniProtKB
Enzymatic activity 
It requires the following cofactor
 Zn(2+) : Binds 1 zinc ion per subunit.  
1
  • UniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Ribosome  hsa03010+6167  
According to Reactome, this protein belongs to the following pathways:
Eukaryotic Translation Termination  R-HSA-72764  
Formation of a pool of free 40S subunits  R-HSA-72689  
GTP hydrolysis and joining of the 60S ribosomal subunit  R-HSA-72706  
L13a-mediated translational silencing of Ceruloplasmin expression  R-HSA-156827  
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)  R-HSA-975957  
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)  R-HSA-975956  
Peptide chain elongation  R-HSA-156902  
SRP-dependent cotranslational protein targeting to membrane  R-HSA-1799339  
Viral mRNA Translation  R-HSA-192823  
 

Keywords

Molecular function 
Ribonucleoprotein  definition   [KW-0687]
Ribosomal protein  definition   [KW-0689]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: RPL37
GenomeRNAi: 6167
PRO: PR:P61927