HBA2 - Hemoglobin subunit alpha - human protein (Function)
 
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Protein
Gene
References

 
HBA1 »  Hemoglobin subunit alpha
 
Protein also known as:  Hemoglobin alpha chain.
Gene name:  HBA1 ; HBA2
Family name: Globin
Entry whose protein(s) existence is based on evidence at protein level
extend overview
2 336 1
GENE REF ISO

Function

 show evidences
Overview 
Involved in oxygen transport from the lung to the various peripheral tissues.  
  • CuratedUniProtKB
GO molecular function 
Contributes to haptoglobin bindingdefinition[GO:0031720]  
1
  • IDABHF-UCL
Heme bindingdefinition[GO:0020037] silver  
  • IEAInterPro 2 GO
Iron ion bindingdefinition[GO:0005506] silver  
  • IEAInterPro 2 GO
Oxygen bindingdefinition[GO:0019825] silver  
  • IEAInterPro 2 GO
Oxygen transporter activitydefinition[GO:0005344]  
  • IEAUniProtKB KW
Contributes to peroxidase activitydefinition[GO:0004601]  
1
  • IDABHF-UCL
Protein bindingdefinition[GO:0005515]  
10
  • IPIIntAct
  • IPIUniProtKB
GO biological process 
Hydrogen peroxide catabolic processdefinition[GO:0042744]  
1
  • IDABHF-UCL
Oxidation-reduction processdefinition[GO:0055114]  
1
  • IDAGOC
Oxygen transportdefinition[GO:0015671]  
1
  • TASUniProtKB
Positive regulation of cell deathdefinition[GO:0010942]  
1
  • IDABHF-UCL
Protein heterooligomerizationdefinition[GO:0051291]  
1
  • IDABHF-UCL
Response to hydrogen peroxidedefinition[GO:0042542]  
1
  • IDABHF-UCL
Pathways 
According to KEGG, this protein belongs to the following pathways:
African trypanosomiasis  hsa05143+3040  
African trypanosomiasis  hsa05143+3039  
Malaria  hsa05144+3040  
Malaria  hsa05144+3039  
According to Reactome, this protein belongs to the following pathways:
Binding and Uptake of Ligands by Scavenger Receptors  REACT_160300  
Metabolism  REACT_111217  
Note 
Gives blood its red color.  
  • CuratedUniProtKB
 

Keywords

Biological process 
Oxygen transport  definition   [KW-0561]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links