PITX1 - Pituitary homeobox 1 - human protein (Function)
 
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Protein
Gene
References

 
PITX1 »  Pituitary homeobox 1
 
Protein also known as:  Paired-like homeodomain transcription factor 1.
Gene name:  PITX1
Family name: Paired homeobox » Bicoid
Entry whose protein(s) existence is based on evidence at protein level
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1 39 1
GENE REF ISO

Function

 show evidences
Overview 
May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.  
  • CuratedUniProtKB
GO molecular function 
RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcriptiondefinition[GO:0001190] silver  
  • IEAOrtholog Compara
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
  • IEAInterPro 2 GO
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAOrtholog Compara
GO biological process 
Anatomical structure morphogenesisdefinition[GO:0009653]  
1
  • TASPINC
Branchiomeric skeletal muscle developmentdefinition[GO:0014707] silver  
  • IEAOrtholog Compara
Cartilage developmentdefinition[GO:0051216] silver  
  • IEAOrtholog Compara
Embryonic hindlimb morphogenesisdefinition[GO:0035116] silver  
  • IEAOrtholog Compara
Myoblast fate commitmentdefinition[GO:0048625] silver  
  • IEAOrtholog Compara
Pituitary gland developmentdefinition[GO:0021983] silver  
  • IEAOrtholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
  • IEAOrtholog Compara
Skeletal system developmentdefinition[GO:0001501]  
1
  • TASPINC
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: PITX1
GenomeRNAi: 5307
PRO: PR:P78337