CCNA1 - Cyclin-A1 - human protein (Function)
 
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Protein
Gene
References

 
CCNA1 »  Cyclin-A1
 
Gene name:  CCNA1
Family name: Cyclin » Cyclin AB
Entry whose protein(s) existence is based on evidence at protein level
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1 58 3
GENE REF ISO

Function

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Overview 
May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.  
1
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
Protein kinase bindingdefinition[GO:0019901] silver  
  • IEAInterPro 2 GO
GO biological process 
Male meiosis Idefinition[GO:0007141]  
1
  • TASPINC
Mitosisdefinition[GO:0007067]  
  • IEAUniProtKB KW
Regulation of cyclin-dependent protein serine/threonine kinase activitydefinition[GO:0000079] silver  
  • IEAInterPro 2 GO
Spermatogenesisdefinition[GO:0007283]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Acute myeloid leukemia  hsa05221+8900  
Cell cycle  hsa04110+8900  
Pathways in cancer  hsa05200+8900  
Progesterone-mediated oocyte maturation  hsa04914+8900  
According to Reactome, this protein belongs to the following pathways:
Cdc20:Phospho-APC/C mediated degradation of Cyclin A  REACT_6850  
Cell Cycle  REACT_115566  
Cellular responses to stress  REACT_120956  
DNA Replication  REACT_383  
 

Keywords

Biological process 
Cell cycle  definition   [KW-0131]
Cell division  definition   [KW-0132]
Mitosis  definition   [KW-0498]
Molecular function 
Cyclin  definition   [KW-0195]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Cyclin_A1
GenomeRNAi: 8900
PRO: PR:P78396