CXCL6 - C-X-C motif chemokine 6 - human protein (Function)
 
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Protein
Gene
References

 
CXCL6 »  C-X-C motif chemokine 6
 
Protein also known as:  Granulocyte chemotactic protein 2 (GCP-2). Cleaved into:  Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3.
Gene name:  CXCL6
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 24 1
GENE REF ISO

Function

 show evidences
Overview 
Chemotactic for neutrophil granulocytes.  
3
  • CuratedUniProtKB
GO molecular function 
Chemokine activitydefinition[GO:0008009] silver  
  • IEAInterPro 2 GO
Heparin bindingdefinition[GO:0008201]  
  • IEAUniProtKB KW
GO biological process 
Cell chemotaxisdefinition[GO:0060326]  
1
  • TASGOC
Cell-cell signalingdefinition[GO:0007267]  
1
  • TASPINC
Chemotaxisdefinition[GO:0006935]  
1
  • TASPINC
Immune responsedefinition[GO:0006955] silver  
  • IEAInterPro 2 GO
Inflammatory responsedefinition[GO:0006954]  
1
  • TASPINC
Signal transductiondefinition[GO:0007165]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Chemokine signaling pathway  hsa04062+6372  
Cytokine-cytokine receptor interaction  hsa04060+6372  
Pertussis  hsa05133+6372  
Rheumatoid arthritis  hsa05323+6372  
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Biological process 
Chemotaxis  definition   [KW-0145]
Molecular function 
Cytokine  definition   [KW-0202]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 6372
PRO: PR:P80162