NUCB2 - Nucleobindin-2 - human protein (Function)
 
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Protein
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References

 
NUCB2 »  Nucleobindin-2
 
Protein also known as:  Gastric cancer antigen Zg4. Cleaved into:  Nesfatin-1.
Gene name:  NUCB2
Family name: Nucleobindin
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Calcium-binding protein. May have a role in calcium homeostasis.  
  • CuratedUniProtKB
Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Calcium ion bindingdefinition[GO:0005509] silver  
  • IEAOrtholog Compara
DNA bindingdefinition[GO:0003677]  
  • IEAUniProtKB KW
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Note 
NEFA stands for N=DNA-binding; EF=EF-hand; A=Acidic region.  
  • CuratedUniProtKB
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: NUCB2
GenomeRNAi: 4925
PRO: PR:P80303