GALK2 - N-acetylgalactosamine kinase - human protein (Function)
 
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Protein
Gene
References

 
GALK2 »  N-acetylgalactosamine kinase
 
Gene name:  GALK2
Family name: GHMP kinase » GalK
Entry whose protein(s) existence is based on evidence at protein level
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1 22 2
GENE REF ISO

Function

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Overview 
Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates.  
2
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Galactokinase activitydefinition[GO:0004335]  
1
  • IDAUniProtKB
N-acetylgalactosamine kinase activitydefinition[GO:0033858]  
  • IEAEC 2 GO
GO biological process 
Carbohydrate metabolic processdefinition[GO:0005975]  
1
  • TASPINC
Carbohydrate phosphorylationdefinition[GO:0046835] silver  
  • IEAInterPro 2 GO
Galactose metabolic processdefinition[GO:0006012] silver  
  • IEAInterPro 2 GO
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.1.157: ATP + N-acetyl-alpha-D-galactosamine ADP + N-acetyl-alpha-D-galactosamine 1-phosphate.  
  • CuratedUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
Amino sugar and nucleotide sugar metabolism  hsa00520+2585  
Galactose metabolism  hsa00052+2585  
Metabolic pathways  hsa01100+2585  
 

Keywords

Molecular function 
Kinase  definition   [KW-0418]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 2585
PRO: PR:Q01415