FABP5 - Fatty acid-binding protein, epidermal - human protein (Function)
 
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FABP5 »  Fatty acid-binding protein, epidermal
 
Protein also known as:  Psoriasis-associated fatty acid-binding protein homolog (PA-FABP).
Gene name:  FABP5
Entry whose protein(s) existence is based on evidence at protein level
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1 49 1
GENE REF ISO

Function

 show evidences
Overview 
High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the fatty acid binding protein (fabp) family  8.A.33.1.1  
GO molecular function 
Fatty acid bindingdefinition[GO:0005504] silver  
  • IEAOrtholog Compara
Lipid bindingdefinition[GO:0008289]  
1
  • TASPINC
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
Transporter activitydefinition[GO:0005215] silver  
  • IEAInterPro 2 GO
GO biological process 
Epidermis developmentdefinition[GO:0008544]  
1
  • TASPINC
Glucose metabolic processdefinition[GO:0006006] silver  
  • IEAOrtholog Compara
Glucose transportdefinition[GO:0015758] silver  
  • IEAOrtholog Compara
Lipid metabolic processdefinition[GO:0006629]  
1
  • TASPINC
Phosphatidylcholine biosynthetic processdefinition[GO:0006656] silver  
  • IEAOrtholog Compara
Response to woundingdefinition[GO:0009611] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
PPAR signaling pathway  hsa03320+2171  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: FABP5
GenomeRNAi: 2171
PRO: PR:Q01469