FABP5 - Fatty acid-binding protein, epidermal - human protein (Function)
 
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FABP5 »  Fatty acid-binding protein, epidermal
 
Protein also known as:  Psoriasis-associated fatty acid-binding protein homolog (PA-FABP).
Gene name:  FABP5
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.  
1
  • UniProtKB
According to TCDB this is a transporter from family:
the fatty acid binding protein (fabp) family  8.A.33.1.1  
GO molecular function 
Fatty acid bindingdefinition[GO:0005504] silver  
1
  • Ortholog Compara
Lipid bindingdefinition[GO:0008289]  
1
  • PINC
Protein bindingdefinition[GO:0005515]  
1
  • UniProtKB
Transporter activitydefinition[GO:0005215] silver  
1
  • InterPro 2 GO
GO biological process 
Epidermis developmentdefinition[GO:0008544]  
1
  • PINC
Glucose metabolic processdefinition[GO:0006006] silver  
1
  • Ortholog Compara
Glucose transportdefinition[GO:0015758] silver  
1
  • Ortholog Compara
Lipid metabolic processdefinition[GO:0006629]  
1
  • PINC
Phosphatidylcholine biosynthetic processdefinition[GO:0006656] silver  
1
  • Ortholog Compara
Response to woundingdefinition[GO:0009611] silver  
1
  • Ortholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
PPAR signaling pathway  hsa03320+2171  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: FABP5
GenomeRNAi: 2171
PRO: PR:Q01469