AKAP17A - A-kinase anchor protein 17A - human protein (Function)
 
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AKAP17A »  A-kinase anchor protein 17A  (AKAP-17A)
 
Protein also known as:  Splicing factor, arginine/serine-rich 17A.
Gene name:  AKAP17A
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.  
3
  • UniProtKB
GO molecular function 
Nucleotide bindingdefinition[GO:0000166] silver  
1
  • InterPro 2 GO
Poly(A) RNA bindingdefinition[GO:0044822]  
1
  • UniProtKB
Protein bindingdefinition[GO:0005515]  
2
  • IntAct
Protein kinase A bindingdefinition[GO:0051018]  
1
  • UniProtKB
GO biological process 
B cell activationdefinition[GO:0042113]  
1
  • UniProtKB
mRNA processingdefinition[GO:0006397]  
1
  • UniProtKB KW
Regulation of RNA splicingdefinition[GO:0043484]  
1
  • UniProtKB
Regulation of transcription, DNA-templateddefinition[GO:0006355]  
1
  • UniProtKB
RNA splicingdefinition[GO:0008380]  
1
  • UniProtKB KW
Signal transductiondefinition[GO:0007165]  
1
  • UniProtKB
Note 
The gene coding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.  
1
  • UniProtKB
Caution 
Was originally thought to be a cell surface protein involved in B-cell activation.  
2
  • UniProtKB
 

Keywords

Biological process 
mRNA processing  definition   [KW-0507]
mRNA splicing  definition   [KW-0508]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SFRS17A
GenomeRNAi: 8227
PRO: PR:Q02040