PAX5 - Paired box protein Pax-5 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
PAX5 »  Paired box protein Pax-5
 
Protein also known as:  B-cell-specific transcription factor (BSAP).
Gene name:  PAX5
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 106 11
GENE REF ISO

Function

 show evidences
Overview 
May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.  
1
  • UniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
RNA polymerase II core promoter proximal region sequence-specific DNA bindingdefinition[GO:0000978] silver  
1
  • Ortholog Compara
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptiondefinition[GO:0001077] silver  
1
  • Ortholog Compara
GO biological process 
Humoral immune responsedefinition[GO:0006959]  
1
  • PINC
Multicellular organismal developmentdefinition[GO:0007275]  
1
  • PINC
Negative regulation of histone H3-K9 methylationdefinition[GO:0051573] silver  
1
  • Ortholog Compara
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122] silver  
1
  • Ortholog Compara
Nervous system developmentdefinition[GO:0007399]  
1
  • UniProtKB KW
Organ morphogenesisdefinition[GO:0009887]  
1
  • PINC
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
1
  • Ortholog Compara
Skeletal muscle cell differentiationdefinition[GO:0035914] silver  
1
  • Ortholog Compara
Spermatogenesisdefinition[GO:0007283]  
1
  • UniProtKB KW
Transcription from RNA polymerase II promoterdefinition[GO:0006366]  
1
  • PINC
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Neurogenesis  definition   [KW-0524]
Spermatogenesis  definition   [KW-0744]
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: PAX5
GenomeRNAi: 5079
PRO: PR:Q02548