NHLH1 - Helix-loop-helix protein 1 - human protein (Function)
 
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Protein
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References

 
NHLH1 »  Helix-loop-helix protein 1  (HEN-1)
 
Protein also known as:  Class A basic helix-loop-helix protein 35 (bHLHa35).
Gene name:  NHLH1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.  
  • CuratedUniProtKB
GO molecular function 
Protein dimerization activitydefinition[GO:0046983] silver  
  • IEAInterPro 2 GO
RNA polymerase II regulatory region sequence-specific DNA bindingdefinition[GO:0000977]  
1
  • IDANTNU_SB
RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptiondefinition[GO:0001228]  
1
  • IDANTNU_SB
GO biological process 
Cell differentiationdefinition[GO:0030154]  
  • IEAUniProtKB KW
Central nervous system developmentdefinition[GO:0007417]  
1
  • TASPINC
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944]  
1
  • IDANTNU_SB
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: NHLH1
GenomeRNAi: 4807
PRO: PR:Q02575