CREB5 - Cyclic AMP-responsive element-binding protein 5 - human protein (Function)
 
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CREB5 »  Cyclic AMP-responsive element-binding protein 5  (CREB-5)
 
Protein also known as:  CRE-BPa.
Gene name:  CREB5
Family name: bZIP
Entry whose protein(s) existence is based on evidence at protein level
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1 29 4
GENE REF ISO

Function

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Overview 
Binds to the cAMP response element and activates transcription.  
1
  • CuratedUniProtKB
GO molecular function 
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptiondefinition[GO:0001077] silver  
  • IEAOrtholog Compara
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
  • IEAInterPro 2 GO
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700]  
1
  • IDAUniProtKB
GO biological process 
Adipose tissue developmentdefinition[GO:0060612] silver  
  • IEAOrtholog Compara
Fat cell differentiationdefinition[GO:0045444] silver  
  • IEAOrtholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
  • IEAOrtholog Compara
Positive regulation of transcription, DNA-templateddefinition[GO:0045893]  
1
  • IDAUniProtKB
Transcription from RNA polymerase II promoterdefinition[GO:0006366]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Cholinergic synapse  hsa04725+9586  
Dopaminergic synapse  hsa04728+9586  
Huntington's disease  hsa05016+9586  
Prostate cancer  hsa05215+9586  
Vasopressin-regulated water reabsorption  hsa04962+9586  
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CREB5
GenomeRNAi: 9586
PRO: PR:Q02930