POU3F1 - POU domain, class 3, transcription factor 1 - human protein (Function)
 
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Protein
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References

 
POU3F1 »  POU domain, class 3, transcription factor 1
 
Protein also known as:  Octamer-binding transcription factor 6 (OTF-6).
Gene name:  POU3F1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Thought to be involved in early embryogenesis and neurogenesis.  
  • CuratedUniProtKB
GO molecular function 
RNA polymerase II transcription coactivator activitydefinition[GO:0001105] silver  
  • IEAOrtholog Compara
Sequence-specific DNA bindingdefinition[GO:0043565]  
1
  • IDAMGI
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAInterPro 2 GO
GO biological process 
Axon ensheathmentdefinition[GO:0008366]  
1
  • TASPINC
Forebrain developmentdefinition[GO:0030900] silver  
  • IEAOrtholog Compara
Keratinocyte differentiationdefinition[GO:0030216] silver  
  • IEAOrtholog Compara
Myelination in peripheral nervous systemdefinition[GO:0022011] silver  
  • IEAOrtholog Compara
Positive regulation of gene expressiondefinition[GO:0010628]  
  • ISSOrtholog Curator
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944]  
  • IEAOrtholog Compara
Positive regulation of transcription, DNA-templateddefinition[GO:0045893]  
  • ISSOrtholog Curator
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: POU3F1
GenomeRNAi: 5453
PRO: PR:Q03052