CHRNE - Acetylcholine receptor subunit epsilon - human protein (Sequence)
 
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CHRNE »  Acetylcholine receptor subunit epsilon
 
Gene name:  CHRNE
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 34 1
GENE REF ISO

Displayed isoform: Iso 1

 
 
Isoform Iso 1   493 aaMass: 54697 Da,  pI: 5.15
MARAPLGVLL LLGLLGRGVG KNEELRLYHH LFNNYDPGSR PVREPEDTVT ISLKVTLTNL ISLNEKEETL TTSVWIGIDW QDYRLNYSKD DFGGIETLRV PSELVWLPEI VLENNIDGQF GVAYDANVLV YEGGSVTWLP PAIYRSVCAV EVTYFPFDWQ NCSLIFRSQT YNAEEVEFTF AVDNDGKTIN KIDIDTEAYT ENGEWAIDFC PGVIRRHHGG ATDGPGETDV IYSLIIRRKP LFYVINIIVP CVLISGLVLL AYFLPAQAGG QKCTVSINVL LAQTVFLFLI AQKIPETSLS VPLLGRFLIF VMVVATLIVM NCVIVLNVSQ RTPTTHAMSP RLRHVLLELL PRLLGSPPPP EAPRAASPPR RASSVGLLLR AEELILKKPR SELVFEGQRH RQGTWTAAFC QSLGAAAPEV RCCVDAVNFV AESTRDQEAT GEEVSDWVRM GNALDNICFW AALVLFSVGS SLIFLGAYFN RVPDLPYAPC IQP

Keywords

Coding sequence diversity 
Polymorphism  definition   [KW-0621]
Domain 
Signal  definition   [KW-0732]
Transmembrane  definition   [KW-0812]
Transmembrane helix  definition   [KW-1133]
PTM 
Disulfide bond  definition   [KW-1015]
Glycoprotein  definition   [KW-0325]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Family and domain databases
Gene3D: 1.20.120.370
Gene3D: 2.70.170.10
InterPro: IPR018000 [ Neurotransmitter ion chnl CS ]
InterPro: IPR006201 [ Neur channel ]
InterPro: IPR006029 [ Neurotrans-gated channel TM ]
InterPro: IPR006202 [ Neur chan lig-bd ]
InterPro: IPR027361 [ Acetylcholine rcpt TM ]
InterPro: IPR002394 [ Nicotinic acetylcholine rcpt ]
PANTHER: PTHR18945 [ PTHR18945 ]
Pfam: PF02931 [ Neur chan LBD ]
Pfam: PF02932 [ Neur chan memb ]
PRINTS: PR00252 [ NRIONCHANNEL ]
PRINTS: PR00254 [ NICOTINICR ]
PROSITE: PS00236 [ NEUROTR ION CHANNEL ]
SUPFAM: SSF90112 [ SSF90112 ]
SUPFAM: SSF63712 [ SSF63712 ]
Genome annotation databases
Ensembl: Transcript: ENST00000293780;  Protein: ENSP00000293780;  Gene: ENSG00000108556.
KEGG: hsa:1145
UCSC: uc002fzk.1
Organism-specific databases
MGI: MGI:87894 [ Chrne ]
Phylogenomic databases
eggNOG: NOG291810
HOGENOM: HOG000006757
HOVERGEN: HBG003756
InParanoid: Q04844
KO: K04817
OMA: AIYRSTC
OrthoDB: EOG7H7925
PhylomeDB: Q04844
Sequence databases
CCDS: CCDS11058.1 [ Q04844-1 ]
EMBL: Genomic DNA:  CH471108 . Translation:  EAW90395.1 .
EMBL: Genomic DNA:  CH471108 . Translation:  EAW90396.1 .
EMBL: Genomic DNA:  AF105999 . Translation:  AAD24503.1 .
EMBL: mRNA:  X66403 . Translation:  CAA47030.1 .
IPI: IPI00029753
PIR: S34775
RefSeq: Protein:  NP_000071.1. Nucleotide sequence:  NM_000080.3.
UniProtKB: Q04844